DeCS Server - List Exact Term

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DeCS

Descritor Inglês:

Activin Receptors

Descritor Espanhol:

Receptores de Activinas

Descritor Português:

Receptores de Ativinas

Sinônimos Inglês:

Activin Receptor-Like Kinases

Categoria:

Definição Inglês:

Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.

Nota Histórica Inglês:

2002; use ACTIVIN RECEPTORS (NM) 1991-2001

Qualificadores Permitidos Inglês:

Número do Registro:

36116

Identificador Único:

D029404

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